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ANA 812. Digestive System III: Liver, Gallbladder & Pancreas. Bethany Cox Sarah Marks Joe Slusher Kara Stebbins. Slide #106 Liver- Pig 4x. Portal Area. Liver Lobule. Slide #106 Liver- Pig. 10x. Central Vein. 40x. Central Vein. Cords of Hepatocytes Liver Sinusoids - PowerPoint PPT Presentation
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Anatomy & Neurobiology
ANA 812Digestive System III:
Liver, Gallbladder & Pancreas
Bethany CoxSarah MarksJoe SlusherKara Stebbins
Anatomy & Neurobiology
Slide #106 Liver- Pig 4x
Portal Area
Liver Lobule
Anatomy & Neurobiology
Slide #106 Liver- Pig
• Central Vein
10x
40xCentral Vein
• Cords of Hepatocytes• Liver Sinusoids• Binucleate Cell
Anatomy & Neurobiology
Slide #106 Liver- Pig4x40x
• Portal Vein• Hepatic Artery• Lymphatic Vessel• Bile Ductule
Anatomy & Neurobiology
Slide #106 Liver- Pig-40X
• Portal Vein• Lymphatic
• Bile Ductule
•Hepatic Artery
Anatomy & Neurobiology
Slide #101 Liver- Human-4X-Note relative lack of connectivetissue.
Anatomy & Neurobiology
Slide #101 Liver- Human-10X
•Central Vein
•Liver Sinusoids
•Hepatocyte Cords
•Lipid Droplets
Anatomy & Neurobiology
Slide #104 Liver- Mouse4x 40x
Portal VeinBile DuctuleLymphatic Vessel
Anatomy & Neurobiology
Liver: Von Kupffer cells-40X
H&E stain (human, slide 101)
Trypan blue stain with neutral red
(monkey, slide 103)Large oval nuclei projecting into sinusoids
Trypan blue phagocytized into granules
Anatomy & Neurobiology
Liver: One Effect of Cirrhosis-40X
Normal liver (H&E stain, human, slide 101)
Cirrhosis (Masson’s trichome stain,human, slide 107)
Vacuolated hepatocyte cytoplasm
Bile canaliculi
Anatomy & Neurobiology
Liver: Another Effect of Cirrhosis-4X
Normal liver (H&E stain, human, slide 101)
Cirrhosis (Masson’s trichome stain,human, slide 107)
Blue-staining collagen
(fewer hepatocytes, more CT)
Anatomy & Neurobiology
Slide #178 – Pancreas and Suprarenal Gland – Monkey
(Azan Stain) – 4X• Pancreatic
Islets of Langerhans (endocrine portion of the pancreas)
• Ducts– Intercalate
d– Intralobular– Interlobular
Anatomy & Neurobiology
Slide #178 – Pancreas and Suprarenal Gland – Monkey
(Azan Stain) – 40X• Islet of Langerhans
4X
Anatomy & Neurobiology
• More secretory acinar divided into lobules
• Ducts– Intercalated (not
seen at this power)– Intralobular– Interlobular
Slide #178 – Pancreas and Suprarenal Gland – Monkey
(Azan Stain) – 10X
Anatomy & Neurobiology
Slide #104-Gallbladder and liver-10X
•Simple columnar eplithelium
•Lamina propria
•Smooth muscle layer
•Definitive mucosal folds
Monkey, H&E stain
Anatomy & Neurobiology
Slide #105-Gallbladder -10X
•Human specimen after death
•Extremely folded gallbladder mucosa seen here is typical of human gallbadder
Human, H&E stain
Anatomy & Neurobiology
Comparison of Slides #104/#105-10X
Monkey, H&E stain
Human, H&E stain