PARAVAC Vaccines against helminth parasites of

livestock of economic and/or public health significance

Dr. Corpus Cerna Cabrera

(Investigador Adjunto Paravac )

Universidad Nacional de Cajamarca

Perú

Proyecto de Investigación

Objetivo:

Desarrollo de vacunas y sistemas de detección para el control de infecciones

producidas por parásitos de importancia en ganaderia (Ortertagia ostertagi, Haemonchus contortus, Fasciola hepatica, Cooperia onchophora, Dictyocaulus

viviparus, Echinococcus granulosus).

N°Proyecto: 265862

Fecha Inicio: 1 April 2011

Fecha término: 31 March 2015

2 - Participants of PARAVAC Part. Nr Institution Principal investigators

P1 Moredun Research Institute (UK) Dave Knox

Dave Smith

P2 Ghent University (BE) Edwin Claerebout

Peter Geldhof

P3 Flanders Interuniversity Institute

for Biotechnology (BE)

Nico Callewaert

P4 University College, Dublin (IE) Grace Mulcahy

P5 Université Claude Bernard Lyon 1

(FR)

Anne-Françoise Pétavy

P6 University of Hannover (D) Thomas Schnieder

Christina Strube

P7 University of Leiden (NL) Ron Hokke

P8 University of Glasgow (UK) Collette Britton

2 - Participants of PARAVAC Part. Nr Institution Principal investigators

P9 University of Liverpool (UK) Diana Williams

P10 University of Cordoba (ES) Jose Perez

P11 McGill University (CA) John Dalton

P12 Rabat-Institute (MA) Allal Dakkak

P13 University de la Republica (UY) Adriana Esteves

P14 Onderstepoort Veterinary Institute

(ZA)

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P15 University of Sao Paulo (BR) Alessandro Amarante

P16 Iscovent (SE) Gerd Rundstrom

2 - Participants of PARAVAC Part. Nr Institution Principal investigators

P17 University of Zurich (CH) Peter Deplazes

P18 National School of Veterinary

Medicine (TN)

Samia Lahmar

P19 Pfizer Animal Health Fraser Stewart

P20 Laramedia (IE) Gerald Cannon

P21 Universidad Nacional de

Cajamarca (PE)

Pedro Ortiz

P22 Triveritas (IE) Julian Braidwood

P23 Murdoch University (AU) Robert Dobson

Cajamarca

• Milk producing area: 800,000 L/day.

• Fasciola hepatica: Most importan parasite disease.

• Very high prevalences (animals and humans).

• Control: Anthelminthic drugs (Triclabendazole and others).

• Resistance.

• Chemical residues in food chain.

• Health problem.

Bovine fasciolosis in Cajamarca Provinces

Fuente: SENASA, 2007. Ministery of Agriculture, Peru

%

L. Carolina Gonzalez, José Guillermo Esteban, M. Dolores Bargues, M. Adela Valero, Pedro Ortiz, Cesar Náquira, Santiago Mas-Coma. Acta Tropica, In Press, 2011

Human fasciolosis in Cajamarca, Peru

On going research:

• Resistance to Triclabendazole

• Pharmacological quality of drugs

• Chemical residues in milk and cheese

• Control

Organization capabilities

• Faculty of Veterinary Science

• Laboratory of immunology

• Lecturing on immunology

• Basic immunology and parasitology tests

• Vaccine trials

Many thanks